PLECTIN IN SKIN FRAGILITY DISORDERS

Plectin in Skin Fragility Disorders

Plectin is macallan hip flask a multi-faceted, 500 kDa-large protein, which due to its expression in different isoforms and distinct organs acts diversely as a cytoskeletal crosslinker and signaling scaffold.It functions as a mediator of keratinocyte mechanical stability in the skin, primarily through linking intermediate filaments to hemidesmosome

read more


Responses of teachers in Scotland to the reintroduction of the practical project in the advanced higher chemistry curriculum

Many pupils who study chemistry in Scotland and intend to progress to university undertake a final capstone practical research project caravan scissor jack as part of their Advanced Higher chemistry qualification.This project work was suspended for several years due to COVID-19, then reintroduced in 2023/24.We surveyed 47 Scottish teachers during t

read more


Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE).

BackgroundFew studies have monitored late presentation (LP) of HIV infection over the European continent, including Eastern Europe.Study objectives were to explore the impact of LP on AIDS and mortality.Methods and findingsLP was defined in Collaboration of Observational HIV Epidemiological Research Europe (COHERE) as HIV diagnosis with a CD4 count

read more